Leptin inhibits food-deprivation-induced increases in food intake and food hoarding

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Leptin inhibits food-deprivation-induced increases in food intake and food hoarding.

Food deprivation stimulates foraging and hoarding and to a much lesser extent, food intake in Siberian hamsters. Leptin, the anorexigenic hormone secreted primarily from adipocytes, may act in the periphery, the brain, or both to inhibit these ingestive behaviors. Therefore, we tested whether leptin given either intracerebroventricularly or intraperitoneally, would block food deprivation-induce...

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PYY(3-36) into the arcuate nucleus inhibits food deprivation-induced increases in food hoarding and intake

Central administration of neuropeptide Y (NPY) increases food intake in laboratory rats and mice, as well as food foraging and hoarding in Siberian hamsters. The NPY-Y1 and Y5 receptors (Rs) within the hypothalamus appear sufficient to account for these increases in ingestive behaviors. Stimulation of NPY-Y2Rs in the Arcuate nucleus (Arc) has an anorexigenic effect as shown by central or periph...

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Peptides that Regulate Food Intake Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters

Buckley, Carolyn A., and Jill E. Schneider. Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters. Am J Physiol Regul Integr Comp Physiol 285: R1021–R1029, 2003. First published May 1, 2003; 10.1152/ajpregu.00488.2002.—Compensatory increases in food intake are commonly observed after a period of food deprivation in many species, including laboratory...

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Anti-ghrelin Spiegelmer inhibits exogenous ghrelin-induced increases in food intake, hoarding, and neural activation, but not food deprivation-induced increases.

Circulating concentrations of the stomach-derived "hunger-peptide" ghrelin increase in direct proportion to the time since the last meal. Exogenous ghrelin also increases food intake in rodents and humans, suggesting ghrelin may increase post-fast ingestive behaviors. Food intake after food deprivation is increased by laboratory rats and mice, but not by humans (despite dogma to the contrary) o...

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Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters.

Compensatory increases in food intake are commonly observed after a period of food deprivation in many species, including laboratory rats and mice. Thus it is interesting that Syrian hamsters fail to increase food intake after a period of food deprivation, despite a fall in plasma leptin concentrations similar to those seen in food-deprived rats and mice. In previous laboratory studies, food-de...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

سال: 2008

ISSN: 0363-6119,1522-1490

DOI: 10.1152/ajpregu.90512.2008